Saints vs Titans Prediction — AI Finds CAN'T MISS NFL Lines & Props (Dec 28)
Updated: 2025-12-21T02:28:40.156150ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
The New Orleans Saints (5–10) travel to Nissan Stadium to face the Tennessee Titans (3–12) on Sunday, December 28, 2025, in a Week 17 AFC South matchup where New Orleans looks to build on a three-game winning streak. The Titans have struggled throughout 2025, but with rookie quarterback Cam Ward showing growth, this game could offer competitive moments as both teams continue shaping their rebuilding outlooks.
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Dec 28, 2025
Start Time: 2:00 PM EST
Venue: Nissan Stadium
Titans Record: (3-12)
Saints Record: (5-10)
OPENING ODDS
NO Moneyline: -150
TEN Moneyline: +127
NO Spread: -2.5
TEN Spread: +2.5
Over/Under: 39.5
NO
Betting Trends
- The Saints have covered the spread seven times this season, reflecting that while their overall record is sub-.500, they frequently stay competitive relative to expectations across matchups, including as slight favorites.
TEN
Betting Trends
- Tennessee has had difficulty covering the spread consistently, with the Titans’ 3–12 mark and frequent deficits leading to mixed ATS results and few reliable cover opportunities at home.
MATCHUP TRENDS
- Head-to-head meetings between these clubs have often been close, with nine of their all-time regular-season games decided by a touchdown or less, suggesting this rivalry tends toward tighter scoring than records imply.
NO vs. TEN
Best Prop Bet
- Remi's searched hard and found the best prop for this matchup: C. Olave over 67.5 Receiving Yards.
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New Orleans vs Tennessee Prediction & Odds:
Free NFL Betting Insights for 12/28/25
The Week 17 matchup between the New Orleans Saints and the Tennessee Titans on December 28, 2025, in Nashville pits a Saints squad enjoying late-season momentum against a rebuilding Titans franchise aiming to close its campaign with a competitive effort. New Orleans has surged in December thanks to a three-game win streak, highlighted by improved offensive rhythm and opportunistic defense, which has helped the team navigate a challenging 5–10 season with a late push that could serve as a springboard into 2026. Quarterback Tyler Shough, New Orleans’ rookie signal-caller, has been at the center of that surge, showing poise and growth that has coincided with the Saints’ recent victories, including a strong performance against the Jets that saw him throw for over 300 yards and help the team sustain long, efficient drives. Meanwhile, wide receiver Chris Olave has delivered an excellent campaign, eclipsing 1,000 receiving yards and serving as Shough’s primary downfield threat, which has stretched defenses and opened opportunities for complementary players. Defensively, the Saints have tightened coverages and limited explosive plays, allowing their secondary to create turnovers and their front seven to apply pressure at timely moments. On the opposite sideline, Tennessee enters this season finale with a 3–12 record that belies signs of growth, particularly under rookie quarterback Cam Ward, who has shown flashes of efficiency and an ability to orchestrate scoring drives despite playing behind a rebuilding supporting cast.
The Titans’ defense, anchored by a strong pass rush led by Jeffery Simmons and disciplined tacklers like Cedric Gray, has created pressure and occasional disruption that can tilt game momentum, even against more prolific offenses. In this matchup, the trenches and situational football will be decisive — New Orleans must protect Shough and sustain drives to keep Tennessee’s defense from pinning its ears back and forcing negative plays, while the Titans will attempt to keep the Saints off balance through pressure packages and controlled run-pass balance that eats up clock and limits possessions. Special teams and third-down execution could also become pivotal; converting red-zone opportunities into touchdowns while limiting field goals will amplify scoring margins, particularly in a game where historical matchups suggest tight finishes. Weather, crowd energy, and late-season intensity further underscore the importance of discipline, with ball security and turnover margin likely determining whether New Orleans extends its win streak or Tennessee exits with a rejuvenating performance that builds belief heading into the offseason.
Get live NFL odds and precise AI NFL picks, predictions, and cover probabilities.
Surgical Shough.
— New Orleans Saints (@Saints) December 22, 2025
32/49 for 308 yards, the first 300-yard game for 6️⃣
📺 https://t.co/KlYFEtUtwd pic.twitter.com/BSHNFi3Or7
New Orleans Saints NFL Preview
The New Orleans Saints arrive in Nashville on December 28, 2025 with tangible momentum and the opportunity to cap a challenging season with a fourth consecutive win that underscores late-season growth and resilience. After starting 0–4 and enduring injuries on both sides of the ball, the Saints have turned their season into a platform for youth development and competitive balance, exemplified by the steady progression of rookie quarterback Tyler Shough, whose recent performances have displayed increased accuracy, timing, and leadership under center. Wide receiver Chris Olave has been a dependable target throughout the season, surpassing 1,000 yards and providing a reliable scoring threat that helps stretch defenses and open underneath routes for emerging playmakers. New Orleans’ offensive scheme emphasizes a balanced attack that utilizes play action, controlled tempo, and strategic runs that set up manageable third-down situations — a philosophy that has kept the Saints competitive even when facing more explosive offenses. Defensively, New Orleans has found strength in its secondary and front seven, tightening coverage in critical moments and creating turnovers that stifle opponent momentum.
The Saints’ ability to limit explosive plays, defend intermediate routes, and pressure opposing quarterbacks has been instrumental in their three-game win streak, with key contributions from young defenders who have stepped into expanded roles. Against the Titans, New Orleans must protect its young quarterback from disruptive pass rushes and sustain drives that keep Tennessee’s defenders on the field and away from their playmaking rotations. Red-zone efficiency remains a priority; converting opportunities into touchdowns rather than settling for field goals can make the difference in a game projected to have modest scoring but tight margins. Special teams execution also deserves attention, as field position and kicker reliability can swing momentum in low-scoring contests. With discipline, balanced offensive execution, and opportunistic defense, the Saints are positioned to win on the road and carry late-season confidence into the offseason narrative that this 2025 campaign — despite its challenges — set a foundation for future consistency and growth.
Credit: USA TODAY/IMAGN
Tennessee Titans NFL Preview
The Tennessee Titans close their 2025 season at Nissan Stadium on December 28 as the home underdog against the New Orleans Saints, seeking to leverage the energy of their final home game to compete with pride and evaluate core elements of their roster moving forward. Tennessee’s campaign has been defined by growth and adversity, with a 3–12 record that belies encouraging individual development, particularly at quarterback where rookie Cam Ward has taken meaningful steps forward. Ward’s recent play includes his highest passer rating of the season — a mark of progress as he finds rhythm with his receivers and manages the game more effectively each week, even as Tennessee’s offense has lacked depth in key pass-catching roles. The Titans’ defense has been a relative bright spot, with a pass rush led by Jeffery Simmons consistently generating pressure and helping create negative plays that keep opponents off balance; Tennessee’s ability to rotate defenders and disguise looks has yielded sacks and disrupted timing, especially when matched against inexperienced offensive lines. In run defense, the Titans have worked to contain opponents’ ground games with disciplined pursuit angles, which has forced teams into third-and-long situations that Tennessee’s front seven has relished attacking.
At home, the Titans will aim to harness crowd support to amplify that pressure and set a tone that prioritizes physicality and execution across all three phases. Offensively, Tennessee’s approach emphasizes controlled drives that feed into manageable down-and-distance situations, reducing the impact of explosive plays and giving Ward the best chance to make calculated throws rather than forcing high-risk passes. The run game, when established early, offers both a way to control clock and keep the defense rested, crucial for a team that has invested heavily in its pass rush and expects consistent energy from its front seven. Situational football — such as converting third downs and limiting penalties — will be central to Tennessee’s ability to stay competitive, as mistakes have too often translated into momentum swings in close games. If the Titans can play disciplined football, leverage defensive disruption, and force New Orleans into uncomfortable down-and-distance sequences, they can extend drives, shorten the game, and potentially spark a late surge that resonates with fans and sets an optimistic tone for 2026.
That was fun 🏈 pic.twitter.com/SlRrXGqvId
— Tennessee Titans (@Titans) December 23, 2025
New Orleans vs Tennessee Prop Picks (AI)
Remi is pouring through tons of datapoints on each player. In fact, anytime the Saints and Titans play there’s always several intriguing observations to key in on. Not to mention games played at Nissan Stadium in Dec almost always follow normal, predictable patterns.
New Orleans vs Tennessee Prediction (AI)
Remi, our AI sports wizard, has been pouring over exorbitant amounts of data from every past game between the Saints and Titans and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most watching on the trending emphasis human bettors regularly put on New Orleans’s strength factors between a Saints team going up against a possibly strong Titans team. We’ve found the true game analytics might reflect a moderate lean against one Vegas line specifically.
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Below is our current AI New Orleans vs Tennessee picks, computer picks Saints vs Titans, best bets, model edges, confidence ratings.
| DATE | GAME | LEAN | %WIN | UNITS | LEVEL | |
|---|---|---|---|---|---|---|
| ACTIVE PICKS LOCKED - SEE NOW | ||||||
These picks update as information changes—injury reports, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full NFL schedule.
New Orleans Betting Trends
The Saints have covered the spread seven times this season, reflecting that while their overall record is sub-.500, they frequently stay competitive relative to expectations across matchups, including as slight favorites.
Tennessee Betting Trends
Tennessee has had difficulty covering the spread consistently, with the Titans’ 3–12 mark and frequent deficits leading to mixed ATS results and few reliable cover opportunities at home.
Saints vs. Titans Matchup Trends
Head-to-head meetings between these clubs have often been close, with nine of their all-time regular-season games decided by a touchdown or less, suggesting this rivalry tends toward tighter scoring than records imply.
New Orleans vs. Tennessee Game Info
New Orleans vs Tennessee starts on December 28, 2025 at 2:00 PM EST.
Venue: Nissan Stadium.
Spread: Tennessee +2.5
Moneyline: New Orleans -150, Tennessee +127
Over/Under: 39.5
New Orleans: (5-10) | Tennessee: (3-12)
Remi's searched hard and found the best prop for this matchup: C. Olave over 67.5 Receiving Yards.. Prices move—always shop for the best number.
Head-to-head meetings between these clubs have often been close, with nine of their all-time regular-season games decided by a touchdown or less, suggesting this rivalry tends toward tighter scoring than records imply.
NO trend: The Saints have covered the spread seven times this season, reflecting that while their overall record is sub-.500, they frequently stay competitive relative to expectations across matchups, including as slight favorites.
TEN trend: Tennessee has had difficulty covering the spread consistently, with the Titans’ 3–12 mark and frequent deficits leading to mixed ATS results and few reliable cover opportunities at home.
See our latest NFL picks and odds pages for 2025 to compare prices before you bet.
New Orleans vs. Tennessee Odds
Remi is pouring through tons of data points on each team. In fact, anytime the New Orleans vs Tennessee trends are analyzed, there’s always several intriguing angles to key in on. Not to mention games played at extreme hostile environments almost always follow normal, predictable betting trends.
| NO Moneyline | -150 |
|---|---|
| TEN Moneyline | +127 |
| NO Spread | -2.5 |
| TEN Spread | +2.5 |
| Over / Under | 39.5 |
New Orleans vs Tennessee Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
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Jan 17, 2026 4:30PM EST
Buffalo Bills
Denver Broncos
1/17/26 4:30PM
Bills
Broncos
|
–
–
|
-105
-115
|
+1 (-110)
-1 (-110)
|
O 45.5 (-114)
U 45.5 (-106)
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|
Jan 17, 2026 8:00PM EST
San Francisco 49ers
Seattle Seahawks
1/17/26 8PM
49ers
Seahawks
|
–
–
|
+265
-335
|
+7 (-109)
-7 (-110)
|
O 45 (-102)
U 45 (-118)
|
|
|
Jan 18, 2026 3:00PM EST
Houston Texans
New England Patriots
1/18/26 3PM
Texans
Patriots
|
–
–
|
+146
-176
|
+3 (-108)
-3 (-113)
|
O 40.5 (-115)
U 40.5 (-105)
|
|
|
Jan 18, 2026 6:30PM EST
Los Angeles Rams
Chicago Bears
1/18/26 6:30PM
Rams
Bears
|
–
–
|
-200
+167
|
-4 (-110)
+4 (-110)
|
O 48.5 (-110)
U 48.5 (-110)
|
NFL Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers New Orleans Saints vs. Tennessee Titans on December 28, 2025 at Nissan Stadium.
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our NFL odds pages, and compare prices before you place a bet.
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RESULT | |
|---|---|---|---|---|
| HOU@PIT | UNDER 38.5 | 53.4% | 2 | WIN |
| HOU@PIT | AARON RODGERS UNDER 21.5 PASS COMP | 54.5% | 4 | WIN |
| LAC@NE | DRAKE MAYE OVER 0.5 INT THROWN | 56.1% | 6 | WIN |
| BUF@JAC | TRAVIS ETIENNE UNDER 81.5 RUSH + RECV YDS | 54.2% | 4 | LOSS |
| SF@PHI | SF +6.5 | 54.7% | 4 | WIN |
| LAC@NE | LAC +3.5 | 57.1% | 7 | LOSS |
| SF@PHI | UNDER 44 | 53.2% | 3 | WIN |
| BUF@JAC | UNDER 51 | 52.1% | 1 | PUSH |
| LAR@CAR | MATTHEW STAFFORD UNDER 33.5 PASS ATT | 53.5% | 3 | LOSS |
| GB@CHI | CALEB WILLIAMS UNDER 0.5 INT THROWN | 55.1% | 5 | LOSS |
| BAL@PIT | DERRICK HENRY OVER 99.5 RUSH + REC YDS | 55.9% | 5 | WIN |
| DET@CHI | JAHMYR GIBBS ANYTIME TD | 56.8% | 6 | WIN |
| IND@HOU | CJ STROUD OVER 221.5 PASS + RUSH YDS | 55.4% | 5 | LOSS |
| TEN@JAC | JAC -13.5 | 56.3% | 6 | WIN |
| CLE@CIN | CIN -7.5 | 53.8% | 3 | LOSS |
| DAL@NYG | OVER 49.5 | 54.6% | 4 | WIN |
| CAR@TB | BRYCE YOUNG UNDER 0.5 INT | 55.2% | 5 | LOSS |
| SEA@SF | KENNETH WALKER III UNDER 11.5 RUSH ATT | 55.3% | 5 | LOSS |
| CAR@TB | BAKER MAYFIELD OVER 0.5 INT | 54.1% | 4 | WIN |
| SEA@SF | CHRISTIAN MCCAFFREY OVER 5.5 RECEPTIONS | 56.7% | 6 | WIN |
| LAR@ATL | KYLE PITS OVER 54.5 RECV YDS | 55.7% | 5 | LOSS |
| LAR@ATL | BIJAN ROBINSON UNDER 44.5 RECV YDS | 54.3% | 4 | WIN |
| CHI@SF | CALEB WILLIAMS OVER 224.5 PASS YDS | 54.1% | 4 | WIN |
| JAC@IND | MICHAEL PITTMAN OVER 49.5 RECV YDS | 55.2% | 5 | LOSS |
| PIT@CLE | CLE +4.5 | 56.9% | 6 | WIN |
| ARI@CIN | CIN -7 | 58.8% | 8 | WIN |
| TB@MIA | TB -4.5 | 55.2% | 5 | LOSS |
| NYG@LV | NYG -2 | 54.3% | 4 | WIN |
| NE@NYJ | NE -13.5 | 53.9% | 3 | WIN |
| NO@TEN | NO -1 | 56.0% | 5 | WIN |
| NYG@LV | UNDER 41.5 | 53.7% | 3 | LOSS |
| HOU@LAC | CJ STROUD OVER 0.5 INT | 55.5% | 5 | WIN |
| DAL@WAS | DAL -8.5 | 54.1% | 4 | LOSS |
| DEN@KC | RJ HARVEY ANYTIME TD | 54.4% | 4 | WIN |
| DAL@WAS | TERRY MCLAURIN ANYTIME TD | 53.9% | 3 | LOSS |
| SF@IND | BROCK PURDY OVER 0.5 INT | 55.2% | 5 | WIN |
| SF@IND | MICHAEL PITTMAN JR OVER 3.5 RECEPTIONS | 54.2% | 4 | WIN |
| SF@IND | SF -4.5 | 56.8% | 6 | WIN |
| LV@HOU | NICO COLLINS ANYTIME TD | 56.3% | 6 | LOSS |
| LAC@DAL | JAVONTE WILLIAMS UNDER 82.5 RUSH + RECV YDS | 55.2% | 5 | WIN |
| JAC@DEN | TREVOR LAWRENCE UNDER 251.5 PASS + RUSH YDS | 57.4% | 7 | LOSS |
| NE@BAL | OVER 48.5 | 53.2% | 2 | WIN |
| LV@HOU | HOU -14 | 54.6% | 4 | LOSS |
| BUF@CLE | CLE +10.5 | 54.9% | 4 | WIN |
| MIN@NYG | MIN -2.5 | 56.3% | 6 | WIN |
| TB@CAR | TB -3 | 53.1% | 3 | LOSS |
| JAC@DEN | DEN -3.5 | 53.6% | 3 | LOSS |
| KC@TEN | KC -2.5 | 54.6% | 4 | LOSS |
| NE@BAL | NE +3.5 | 56.4% | 6 | WIN |
| GB@CHI | CHI -112 | 54.4% | 2 | WIN |
| GB@CHI | CALEB WILLIAMS UNDER 0.5 INT | 55.2% | 5 | WIN |