The Week 4 matchup between the Washington Commanders and Arizona Cardinals presents an intriguing clash between two teams seeking early-season momentum. Washington comes into this contest with a 2-1 record, fresh off a thrilling 38-33 win over the Cincinnati Bengals. Quarterback Jayden Daniels has been efficient, throwing for over 600 yards and five touchdowns while showcasing his ability to extend plays with his legs.

On the other side, the Cardinals enter with a 1-2 record, following a 20-13 loss to the Detroit Lions. Arizona has been inconsistent, but Kyler Murray’s return from injury has provided a spark for their offense. The Cardinals will rely heavily on Murray and running back James Conner to create opportunities against a Washington defense that has struggled, allowing 29.3 points per game. Washington’s defense will be key in this matchup, particularly in containing the dual-threat capabilities of Murray. If they can generate pressure, their secondary, led by Emmanuel Forbes, will have opportunities to force turnovers. On offense, Daniels’ connection with Terry McLaurin and the resurgence of running back Brian Robinson Jr. will be pivotal in keeping the Commanders’ balanced attack moving. Arizona’s defense, which has allowed 21.3 points per game, will need to find ways to slow down Washington’s high-powered offense. Led by Dennis Gardeck, who has three sacks on the season, the Cardinals will look to disrupt Daniels in the pocket. With the Cardinals slightly favored at home, this game could come down to which team capitalizes on key defensive stops. The Cardinals’ home-field advantage and their recent success ATS against NFC East opponents give them a slight edge, but Washington’s offensive firepower cannot be overlooked.