The matchup between the Louisville Cardinals and Notre Dame Fighting Irish is shaping up to be a crucial battle in Week 5 of the 2024 college football season. Notre Dame, with a 3-1 record, looks to build on their recent defensive dominance, most recently seen in a 28-3 win over Miami (OH). Quarterback Riley Leonard has led a balanced Notre Dame offense, accumulating over 587 passing yards while adding 322 rushing yards and six rushing touchdowns.

The Fighting Irish offense is complemented by their powerful rushing attack, spearheaded by Jeremiyah Love, who has racked up 339 rushing yards and four touchdowns this season. Louisville, undefeated at 3-0, enters this contest with plenty of confidence. Led by quarterback Tyler Shough, who has thrown for 850 yards and 8 touchdowns, the Cardinals have averaged an impressive 47.3 points per game. Louisville’s offense is dynamic, featuring a balanced attack with a solid rushing game led by Isaac Brown, who averages 10.8 yards per carry.

However, Louisville’s defensive unit will be tested against Notre Dame’s physical offensive line and balanced play calling. The key to this game will be whether Louisville’s explosive offense can penetrate Notre Dame’s stout defense, which is allowing just 14.5 points per game. The Cardinals will need to avoid costly turnovers and stay efficient in the red zone if they hope to keep this game close. On the other hand, Notre Dame will likely lean on their ground game and solid defense to control the tempo and grind out a victory.