Louisville vs Duke Prediction — AI Finds CAN'T MISS CBB Lines & Props (Jan 26)
Updated: 2026-01-24T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Jan 26, 2026
Start Time: 7:00 PM EST
Venue:
Blue Devils Record:
Cardinals Record:
OPENING ODDS
LVILLE Moneyline:
DUKE Moneyline:
LVILLE Spread: 0
DUKE Spread:
Over/Under:
LVILLE
Betting Trends
DUKE
Betting Trends
MATCHUP TRENDS
LVILLE vs. DUKE
Best Prop Bet
LIVE CBB ODDS
CBB ODDS COMPARISON
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Louisville vs Duke Prediction & Odds:
Free CBB Betting Insights for 1/26/26
Get live CBB odds and precise AI CBB picks, predictions, and cover probabilities.
Louisville Cardinals CBB Preview
Credit: USA TODAY/IMAGN
Duke Blue Devils CBB Preview
Louisville vs Duke Prop Picks (AI)
AI algorithm Remi is pouring through mountains of stats on each team. In fact, anytime the Cardinals and Blue Devils play there’s always several intriguing angles to key in on. Not to mention games played at in Jan rarely follow normal, predictable betting trends.
Louisville vs Duke Prediction (AI)
Remi, our AI sports algorithm, has been pouring over tons of data from every angle between the Cardinals and Blue Devils and using recursive machine learning and kick-ass AI to crunch the data to a single cover probability.
Oddly enough, we’ve seen the AI has been most watching on the trending emphasis human bettors tend to put on Duke’s strength factors between a Cardinals team going up against a possibly rested Blue Devils team. We’ve found the true game analytics might reflect a slight lean against one Vegas line specifically.
Unlock this in-depth AI prediction and all of our CBB AI picks for FREE now.
Below is our current AI Louisville vs Duke picks, computer picks Cardinals vs Blue Devils, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| CBB | 12/7 | SMU@TEXA&M | UNLOCK THIS PICK | 9 |
VAULT v4
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| CBB | 12/7 | CCTST@NEAST | UNLOCK THIS PICK | 8 |
VAULT v4
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| CBB | 12/7 | WISCGB@WRIGHT | UNLOCK THIS PICK | 6 |
VAULT v2
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| CBB | 12/7 | WEBER@STTOM-MN | UNLOCK THIS PICK | 5 |
EXECUTIVE
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| CBB | 12/7 | LSU@TXTECH | UNLOCK THIS PICK | 10 |
INTEL
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| CBB | 12/7 | UNLV@STNFRD | UNLOCK THIS PICK | 1 |
INTEL
|
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| CBB | 12/7 | TOWSON@UCF | UNLOCK THIS PICK | 0 |
INTEL
|
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| CBB | 12/7 | AF@NAVY | UNLOCK THIS PICK | 0 |
INTEL
|
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| CBB | 12/7 | SANFRAN@MISSST | UNLOCK THIS PICK | 1 |
INTEL
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These picks update as information changes—injury reports, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CBB schedule.
Louisville Betting Trends
Duke Betting Trends
Cardinals vs. Blue Devils Matchup Trends
Louisville vs. Duke Game Info
Louisville vs Duke starts on January 26, 2026 at 7:00 PM EST.
Venue: .
Spread: Duke
Moneyline: Louisville , Duke
Over/Under:
Louisville: | Duke:
. Prices move—always shop for the best number.
LVILLE trend:
DUKE trend:
See our latest CBB picks and odds pages for 2026 to compare prices before you bet.
Louisville vs. Duke Odds
Remi is pouring through loads of stats on each line. In fact, anytime the Louisville vs Duke trends are analyzed, there’s always several intriguing observations to key in on. Not to mention games played at extreme temps almost always follow normal, predictable patterns.
| LVILLE Moneyline | |
|---|---|
| DUKE Moneyline | |
| LVILLE Spread | 0 |
| DUKE Spread | |
| Over / Under |
Louisville vs Duke Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
Dec 8, 2025 6:00PM EST
Lafayette Leopards
Pennsylvania Quakers
12/8/25 6PM
LAFAY
PENN
|
–
–
|
+250
-320
|
+6.5 (-110)
-6.5 (-110)
|
O 152.5 (-110)
U 152.5 (-110)
|
|
|
Dec 8, 2025 7:00PM EST
South Carolina State Bulldogs
Charleston Southern Buccaneers
12/8/25 7PM
SCST
CHARSO
|
–
–
|
-600
|
-10.5 (-110)
|
O 154.5 (-110)
U 154.5 (-110)
|
|
|
Dec 8, 2025 8:00PM EST
Mississippi Valley State Delta Devils
Kansas State Wildcats
12/8/25 8PM
MVSU
KSTATE
|
–
–
|
|
pk
pk
|
O 159 (-110)
U 159 (-110)
|
|
|
Dec 8, 2025 8:00PM EST
Grambling State Tigers
USM Golden Eagles
12/8/25 8PM
GRAMB
USM
|
–
–
|
|
pk
pk
|
O 141 (-110)
U 141 (-110)
|
|
|
Dec 8, 2025 8:00PM EST
Southern Jaguars
Texas Longhorns
12/8/25 8PM
STHRN
TEXAS
|
–
–
|
+1150
-3335
|
+21.5 (-110)
-21.5 (-110)
|
O 155 (-110)
U 155 (-110)
|
|
|
Dec 8, 2025 8:00PM EST
UIW Cardinals
New Orleans Privateers
12/8/25 8PM
UIW
NORL
|
–
–
|
+105
|
+1.5 (-110)
|
O 149.5 (-110)
U 149.5 (-110)
|
|
|
Dec 9, 2025 6:30PM EST
Clemson Tigers
BYU Cougars
12/9/25 6:30PM
CLEM
BYU
|
–
–
|
+185
-225
|
+5.5 (-110)
-5.5 (-110)
|
O 150.5 (-110)
U 150.5 (-110)
|
|
|
Dec 9, 2025 6:30PM EST
Villanova Wildcats
Michigan Wolverines
12/9/25 6:30PM
NOVA
MICH
|
–
–
|
+980
-2100
|
+15 (-110)
-15 (-110)
|
O 148.5 (-110)
U 148.5 (-110)
|
|
|
Dec 9, 2025 7:30PM EST
Illinois Fighting Illini
Ohio State Buckeyes
12/9/25 7:30PM
ILL
OHIOST
|
–
–
|
-180
+140
|
-3.5 (-113)
+3.5 (-113)
|
O 155.5 (-109)
U 155.5 (-117)
|
|
|
Dec 9, 2025 8:30PM EST
Penn State Nittany Lions
Indiana Hoosiers
12/9/25 8:30PM
PSU
IND
|
–
–
|
+810
-1450
|
+13.5 (-105)
-13.5 (-115)
|
O 149.5 (-110)
U 149.5 (-110)
|
|
|
Dec 9, 2025 9:00PM EST
Florida Gators
UConn Huskies
12/9/25 9PM
FLA
UCONN
|
–
–
|
+170
-220
|
+4.5 (-113)
-4.5 (-113)
|
O 145.5 (-115)
U 145.5 (-110)
|
CBB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Louisville Cardinals vs. Duke Blue Devils on January 26, 2026 at .
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CBB odds pages, and compare prices before you place a bet.
|
CBB |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| NCGRN@ECU | NCGRN +7 | 54.5% | 4 | WIN |
| ILL@TENN | ILL +2.5 | 55.6% | 5 | WIN |
| NMEXST@ABIL | NMEXST -2.5 | 56.9% | 6 | LOSS |
| BRYANT@BROWN | BROWN -6.5 | 55.2% | 5 | LOSS |
| UTAHST@SFLA | SFLA +1.5 | 54.0% | 3 | WIN |
| EWASH@DENVER | DENVER -130 | 58.4% | 4 | WIN |
| LVILLE@ARK | LVILLE -2 | 53.8% | 3 | LOSS |
| BALLST@EVAN | BALLST +6.5 | 55.6% | 5 | LOSS |
| NWEST@WISC | NWEST +10.5 | 57.0% | 6 | LOSS |
| SOBAMA@NMEXST | NMEXST +2.5 | 56.3% | 6 | WIN |
| VATECH@SC | SC -118 | 54.7% | 4 | LOSS |
| OKLA@WAKE | WAKE -4 | 56.0% | 6 | LOSS |
| UNC@UK | UNC +6.5 | 53.5% | 2 | WIN |
| GEORGIA@FSU | GEORGIA +1.5 | 54.8% | 5 | WIN |
| TENN@CUSE | CUSE +7.5 | 53.3% | 3 | WIN |
| UAB@MTSU | UAB -125 | 56.7% | 4 | LOSS |
| PORT@STNFRD | PORT +18.5 | 54.9% | 4 | LOSS |
| NH@FAIR | NH +11 | 55.0% | 5 | WIN |
| UCSB@LEHIGH | LEHIGH +10.5 | 54.9% | 4 | WIN |
| BYU@DAYTON | DAYTON +10.5 | 55.1% | 5 | WIN |
| WKY@WICHST | WKY +6.5 | 55.4% | 5 | WIN |
| WISC@TCU | TCU +6.5 | 54.3% | 4 | WIN |
| GTOWN@DAYTON | GTOWN +1.5 | 56.4% | 6 | LOSS |
| STLOU@SNCLRA | STLOU -125 | 57.5% | 4 | WIN |
| TCU@FLA | TCU +12 | 54.7% | 4 | WIN |
| UNLV@RUT | RUT +4.5 | 55.0% | 5 | WIN |
| WKY@SFLA | WKY +8.5 | 56.1% | 7 | WIN |
| NOCOLO@AF | NOCOLO -4.5 | 54.8% | 4 | WIN |
| HARV@BC | HARV +7.5 | 53.8% | 3 | LOSS |
| COLOST@VATECH | UNDER 155.5 | 56.7% | 6 | WIN |
| OLEMISS@IOWA | IOWA -125 | 61.3% | 6 | WIN |
| HOU@TENN | HOU -2.5 | 54.5% | 4 | LOSS |
| UCSD@BRAD | UCSD -110 | 54.5% | 4 | WIN |
| MICH@AUBURN | MICH -4.5 | 53.4% | 2 | WIN |
| MTSU@MCNSE | MTSU +7.5 | 56.5% | 6 | LOSS |
| LAMAR@MONTANA | LAMAR +6.5 | 55.9% | 5 | WIN |
| NWEST@SC | SC +6.5 | 57.5% | 6 | WIN |
| SANFRAN@MINN | SANFRAN -115 | 56.9% | 6 | WIN |
| ARKLR@TEXST | TEXST -6.5 | 56.9% | 6 | WIN |
| GEORGIA@XAVIER | XAVIER +10.5 | 53.1% | 2 | WIN |
| MORGAN@OLDDOM | MORGAN +14.5 | 55.1% | 5 | LOSS |
| NEWORL@FRESNO | NEWORL +7 | 53.4% | 3 | LOSS |
| ARMY@MARIST | ARMY +14 | 55.5% | 5 | WIN |
| MISSST@KSTATE | MISSST -130 | 58.6% | 5 | LOSS |
| MAINE@MERMAK | MERMAK -6.5 | 56.2% | 6 | WIN |
| ARIZ@UCONN | ARIZ +6.5 | 53.3% | 2 | WIN |
| BAMA@ILL | ILL -2.5 | 53.5% | 2 | LOSS |
| SFLA@OKLAST | OKLAST -4 | 54.0% | 2 | WIN |
| ABIL@TEXST | TEXST -125 | 58.0% | 6 | WIN |
| VERMONT@BUFF | VERMONT -2.5 | 55.3% | 5 | LOSS |
| RADFRD@SC | SC -9.5 | 57.2% | 7 | WIN |