Missouri vs Illinois Prediction — AI Finds CAN'T MISS CBB Lines & Props (Dec 22)
Updated: 2025-12-20T03:31:50.923562ZBy Remi at Leans.AI — AI picks for ATS, ML, OU & props
Get key insights, betting trends, and AI-powered predictions to help incorporate into your betting strategies.
GAME INFO
Date: Dec 22, 2025
Start Time: 8:00 PM EST
Venue:
Fighting Illini Record:
Tigers Record:
OPENING ODDS
MIZZOU Moneyline:
ILL Moneyline:
MIZZOU Spread: 0
ILL Spread:
Over/Under:
MIZZOU
Betting Trends
ILL
Betting Trends
MATCHUP TRENDS
MIZZOU vs. ILL
Best Prop Bet
LIVE CBB ODDS
CBB ODDS COMPARISON
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Missouri vs Illinois Prediction & Odds:
Free CBB Betting Insights for 12/22/25
Missouri Tigers CBB Preview
Credit: USA TODAY/IMAGN
Illinois Fighting Illini CBB Preview
Missouri vs. Illinois Prop Picks (AI)
Missouri vs. Illinois Prediction (AI)
Remi, our AI sports genius, has been pouring over millions of data from every simulation between the Tigers and Fighting Illini and using recursive machine learning and cutting-edge AI to crunch the data to a single cover probability.
Remi has been most fixated on the trending emphasis human bettors tend to put on Illinois’s strength factors between a Tigers team going up against a possibly deflated Fighting Illini team. In reality, the true game analytics might reflect a moderate lean against one Vegas line in particular.
Unlock this in-depth AI prediction and all of our CBB AI picks for FREE now.
Below is our current AI Missouri vs Illinois picks, computer picks Tigers vs Fighting Illini, best bets, model edges, confidence ratings.
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DATE | GAME | LEAN | %WIN | UNITS | LEVEL |
|---|---|---|---|---|---|---|
| CBB | 11/13 | PITT@WVU | UNLOCK THIS PICK | 4 |
EXECUTIVE
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| CBB | 11/13 | PURDUE@BAMA | UNLOCK THIS PICK | 3 |
EXECUTIVE
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| CBB | 11/13 | PURDUE@BAMA | UNLOCK THIS PICK | 3 |
INTEL
|
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| CBB | 11/13 | CAL@KSTATE | UNLOCK THIS PICK | 2 |
INTEL
|
|
| CBB | 11/13 | LAMON@HOUBP | UNLOCK THIS PICK | 0 |
INTEL
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| CBB | 11/13 | CORN@LAFAY | UNLOCK THIS PICK | 1 |
INTEL
|
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These picks update as information changes—injury reports, weather, and market movement. Each line shows our model’s fair price, the edge versus the market, and a unit confidence rating (1–10). Odds and availability vary by sportsbook and time. Edges are computed against the listed price; value may change after line moves. Always shop for the best number. See the full CBB schedule.
Tigers Betting Trends
Fighting Illini Betting Trends
Tigers vs. Fighting Illini Matchup Trends
Missouri vs. Illinois Game Info
What time does Missouri vs Illinois start on December 22, 2025?
Missouri vs Illinois starts on December 22, 2025 at 8:00 PM EST.
What are the opening odds for Missouri vs Illinois?
Spread: Illinois
Moneyline: Missouri , Illinois
Over/Under:
What are the records for Missouri vs Illinois?
Missouri: | Illinois:
What is the AI best bet for Missouri vs Illinois?
. Prices move—always shop for the best number.
What are Missouri trending bets?
MIZZOU trend:
What are Illinois trending bets?
ILL trend:
Where can I find AI Picks for Missouri vs Illinois?
See our latest CBB picks and odds pages for 2025 to compare prices before you bet.
Missouri vs. Illinois Odds
Remi is pouring through mountains of stats on each team. In fact, anytime the Missouri vs Illinois trends are analyzed, there’s always several intriguing trends to key in on. Not to mention games played at extreme altitude rarely follow normal, predictable betting trends.
Missouri vs Illinois Opening Odds
MIZZOU Moneyline:
ILL Moneyline:
MIZZOU Spread: 0
ILL Spread:
Over/Under:
Missouri vs Illinois Live Odds
| Games | PTS | ML | SPR | O/U | |
|---|---|---|---|---|---|
|
In Progress
Cornell Big Red
Lafayette Leopards
In Progress
CORN
LAFAY
|
46
40
|
-750
+460
|
-8.5 (-112)
+8.5 (-118)
|
O 170.5 (-122)
U 170.5 (-108)
|
|
|
In Progress
Pittsburgh Panthers
West Virginia Mountaineers
In Progress
PITT
WVU
|
25
39
|
+1500
-7000
|
+14.5 (-114)
-14.5 (-114)
|
O 131.5 (-112)
U 131.5 (-118)
|
|
|
In Progress
San Jose State Spartans
Michigan State Spartans
In Progress
SJST
MICHST
|
13
32
|
|
pk
pk
|
O 137.5 (-112)
U 137.5 (-118)
|
|
|
In Progress
Monmouth Hawks
Seton Hall Pirates
In Progress
MONMTH
SETON
|
0
1
|
+870
-2200
|
+14.5 (-118)
-14.5 (-112)
|
O 133.5 (-112)
U 133.5 (-118)
|
|
|
In Progress
UMass Lowell River Hawks
Columbia Lions
In Progress
MASLOW
CLMBIA
|
6
0
|
+700
-1200
|
+7.5 (-122)
-7.5 (-106)
|
O 159.5 (-122)
U 159.5 (-108)
|
|
|
In Progress
Purdue Boilermakers
Alabama Crimson Tide
In Progress
PURDUE
BAMA
|
6
5
|
+118
-150
|
+2.5 (-125)
-2.5 (-106)
|
O 178.5 (-110)
U 178.5 (-120)
|
|
|
In Progress
Le Moyne Dolphins
Umass Minutemen
In Progress
LMOYNE
UMASS
|
5
7
|
+1200
|
+17.5 (-118)
|
O 157.5 (-112)
U 157.5 (-118)
|
|
|
In Progress
Alcorn State Braves
Howard Bison
In Progress
ALCORN
HOWARD
|
2
2
|
-280
|
-5.5 (-112)
|
O 150.5 (-110)
U 150.5 (-120)
|
|
|
Nov 13, 2025 7:30PM EST
USM Golden Eagles
Grambling State Tigers
11/13/25 7:30PM
USM
GRAMB
|
–
–
|
|
pk
pk
|
O 148.5 (-103)
U 148.5 (-113)
|
|
|
Nov 13, 2025 7:30PM EST
Loyola Chicago Ramblers
Wichita State Shockers
11/13/25 7:30PM
LOYCHI
WICHST
|
–
–
|
|
pk
pk
|
O 153.5 (-109)
U 153.5 (-107)
|
|
|
Nov 13, 2025 8:00PM EST
Charleston Southern Buccaneers
Alabama A&M Bulldogs
11/13/25 8PM
CHARSO
ALA&M
|
–
–
|
+118
-142
|
+1 (-101)
-1 (-111)
|
O 152.5 (-103)
U 152.5 (-113)
|
|
|
Nov 13, 2025 8:00PM EST
Green Bay Phoenix
St. Thomas (MN) Tommies
11/13/25 8PM
GBAY
STTOM
|
–
–
|
+709
-1100
|
+13.5 (-104)
-13.5 (-108)
|
O 150.5 (-103)
U 150.5 (-113)
|
|
|
Nov 13, 2025 8:00PM EST
FIU Panthers
LSU Tigers
11/13/25 8PM
FIU
LSU
|
–
–
|
-7000
|
-21.5 (-106)
|
O 158.5 (-111)
U 158.5 (-105)
|
|
|
Nov 13, 2025 8:00PM EST
UL Monroe Warhawks
Houston Christian Huskies
11/13/25 8PM
MONROE
HOUCHR
|
–
–
|
+385
-520
|
+9 (-108)
-9 (-104)
|
O 143.5 (-113)
U 143.5 (-103)
|
|
|
Nov 13, 2025 9:00PM EST
California Golden Bears
Kansas State Wildcats
11/13/25 9PM
CAL
KSTATE
|
–
–
|
+245
|
+7 (-103)
|
O 164 (-112)
U 164 (-104)
|
|
|
Nov 14, 2025 11:00AM EST
Coppin State Eagles
Central Michigan Chippewas
11/14/25 11AM
COPPIN
CMICH
|
–
–
|
-550
|
-9.5 (-110)
|
O 142.5 (-110)
U 142.5 (-110)
|
|
|
Nov 14, 2025 6:30PM EST
IUPUI Jaguars
Eastern Michigan Eagles
11/14/25 6:30PM
IUPUI
EMICH
|
–
–
|
+340
-450
|
+8.5 (-114)
-8.5 (+102)
|
O 187 (-108)
U 187 (-108)
|
|
|
Nov 14, 2025 6:30PM EST
Lehigh Mountain Hawks
Rutgers Scarlet Knights
11/14/25 6:30PM
LEHGH
RUT
|
–
–
|
+1280
-3500
|
+17.5 (-110)
-17.5 (-110)
|
O 142.5 (-110)
U 142.5 (-110)
|
|
|
Nov 14, 2025 7:00PM EST
Eastern Illinois Panthers
Kentucky Wildcats
11/14/25 7PM
EILL
UK
|
–
–
|
|
+38 (-101)
-38 (-111)
|
O 150 (-108)
U 150 (-108)
|
|
|
Nov 14, 2025 7:00PM EST
Indiana State Sycamores
Duke Blue Devils
11/14/25 7PM
INDST
DUKE
|
–
–
|
|
-36.5 (-106)
|
O 162.5 (-108)
U 162.5 (-108)
|
|
|
Nov 14, 2025 7:00PM EST
Fordham Rams
Iona Gaels
11/14/25 7PM
FORD
IONA
|
–
–
|
+194
-245
|
+5.5 (-106)
-5.5 (-106)
|
O 158.5 (-113)
U 158.5 (-103)
|
|
|
Nov 14, 2025 7:00PM EST
Furman Paladins
Northern Iowa Panthers
11/14/25 7PM
FURMAN
NIOWA
|
–
–
|
+490
-710
|
+11 (-111)
-11 (-101)
|
O 143 (-108)
U 143 (-108)
|
|
|
Nov 14, 2025 7:30PM EST
CSU Bakersfield Roadrunners
Ole Miss Rebels
11/14/25 7:30PM
CSBAK
OLEMISS
|
–
–
|
+3000
-10000
|
+26 (-101)
-26 (-111)
|
O 146 (-108)
U 146 (-108)
|
|
|
Nov 14, 2025 7:30PM EST
Illinois State Redbirds
USC Trojans
11/14/25 7:30PM
ILLST
USC
|
–
–
|
-2800
|
-16.5 (-106)
|
O 157.5 (-113)
U 157.5 (-103)
|
|
|
Nov 14, 2025 8:00PM EST
Maryland Eastern Shore Hawks
Creighton Bluejays
11/14/25 8PM
UMES
CREIGH
|
–
–
|
|
-31.5 (-110)
|
O 143.5 (-110)
U 143.5 (-110)
|
|
|
Nov 14, 2025 8:00PM EST
Milwaukee Panthers
Texas Tech Red Raiders
11/14/25 8PM
MILW
TXTECH
|
–
–
|
|
+27 (+109)
-27 (-122)
|
O 161.5 (-108)
U 161.5 (-108)
|
|
|
Nov 14, 2025 8:00PM EST
Samford Bulldogs
Arkansas Razorbacks
11/14/25 8PM
SAMFRD
ARK
|
–
–
|
+3500
-20000
|
+26 (-111)
-26 (-101)
|
O 162 (-108)
U 162 (-108)
|
|
|
Nov 14, 2025 8:00PM EST
UCF Knights
Texas A&M Aggies
11/14/25 8PM
UCF
TEXAM
|
–
–
|
+460
-650
|
+10.5 (-106)
-10.5 (-106)
|
O 170 (-108)
U 170 (-108)
|
|
|
Nov 14, 2025 8:00PM EST
Xavier Musketeers
Iowa Hawkeyes
11/14/25 8PM
XAVIER
IOWA
|
–
–
|
+860
-1600
|
+14.5 (-104)
-14.5 (-108)
|
O 144.5 (-103)
U 144.5 (-113)
|
|
|
Nov 14, 2025 8:15PM EST
Hampton Pirates
Brown Bears
11/14/25 8:15PM
HAMPT
BROWN
|
–
–
|
+122
-150
|
+2.5 (-106)
-2.5 (-106)
|
O 143.5 (-108)
U 143.5 (-108)
|
|
|
Nov 14, 2025 8:30PM EST
Northwestern Wildcats
DePaul Blue Demons
11/14/25 8:30PM
NWEST
DEPAUL
|
–
–
|
-350
+275
|
-6.5 (-106)
+6.5 (-106)
|
O 138.5 (-108)
U 138.5 (-108)
|
|
|
Nov 14, 2025 9:00PM EST
Cal Poly Mustangs
Montana Grizzlies
11/14/25 9PM
CALPLY
MONT
|
–
–
|
+198
-250
|
+5 (-106)
-5 (-106)
|
O 171 (-108)
U 171 (-108)
|
|
|
Nov 14, 2025 9:00PM EST
North Carolina Central Eagles
North Carolina Tar Heels
11/14/25 9PM
NCCENT
UNC
|
–
–
|
|
+36.5 (-110)
-36.5 (-110)
|
O 160.5 (-110)
U 160.5 (-110)
|
|
|
Nov 14, 2025 9:00PM EST
Georgia Tech Yellow Jackets
Georgia Bulldogs
11/14/25 9PM
GATECH
UGA
|
–
–
|
+810
-1450
|
+14 (-106)
-14 (-106)
|
O 149 (-108)
U 149 (-108)
|
|
|
Nov 14, 2025 9:00PM EST
Providence Friars
Colorado Buffaloes
11/14/25 9PM
PROV
COLO
|
–
–
|
-110
-110
|
-1 (-106)
+1 (-106)
|
O 164 (-108)
U 164 (-108)
|
|
|
Nov 14, 2025 9:00PM EST
Michigan Wolverines
TCU Horned Frogs
11/14/25 9PM
MICH
TCU
|
–
–
|
-350
+275
|
-8.5 (-106)
+8.5 (-106)
|
O 158 (-108)
U 158 (-108)
|
|
|
Nov 14, 2025 9:00PM EST
Colgate Raiders
Illinois Fighting Illini
11/14/25 9PM
COLG
ILL
|
–
–
|
|
+30.5 (-110)
-30.5 (-110)
|
O 163.5 (-110)
U 163.5 (-110)
|
|
|
Nov 14, 2025 9:00PM EST
Tarleton State Texans
Baylor Bears
11/14/25 9PM
TARL
BAYLOR
|
–
–
|
+3000
-10000
|
+26 (-101)
-26 (-111)
|
O 154.5 (-108)
U 154.5 (-108)
|
|
|
Nov 14, 2025 10:00PM EST
Troy Trojans
Loyola Marymount Lions
11/14/25 10PM
TROY
LOYOLA
|
–
–
|
+132
-162
|
+3 (-106)
-3 (-106)
|
O 142.5 (-108)
U 142.5 (-108)
|
|
|
Nov 14, 2025 10:00PM EST
North Texas Mean Green
Saint Mary's Gaels
11/14/25 10PM
NOTEX
STMARY
|
–
–
|
+680
-1100
|
+13.5 (-111)
-13.5 (-101)
|
O 130.5 (-108)
U 130.5 (-108)
|
|
|
Nov 14, 2025 10:00PM EST
Arizona Wildcats
UCLA Bruins
11/14/25 10PM
ARIZ
UCLA
|
–
–
|
-162
+134
|
-3 (-101)
+3 (-111)
|
O 154.5 (-108)
U 154.5 (-108)
|
|
|
Nov 14, 2025 10:30PM EST
Western Illinois Leathernecks
Cal Baptist Lancers
11/14/25 10:30PM
WILL
CALBAP
|
–
–
|
+760
-1400
|
+12.5 (-106)
-12.5 (-106)
|
O 143.5 (-108)
U 143.5 (-108)
|
|
|
Nov 14, 2025 11:00PM EST
Gonzaga Bulldogs
Arizona State Sun Devils
11/14/25 11PM
GONZAG
ARIZST
|
–
–
|
-880
|
-12 (-106)
|
O 162 (-103)
U 162 (-113)
|
|
|
Nov 14, 2025 11:00PM EST
Washington Huskies
Washington State Cougars
11/14/25 11PM
WASH
WASHST
|
–
–
|
-580
|
-9.5 (-101)
|
O 160 (-113)
U 160 (-103)
|
|
|
Nov 15, 2025 12:00AM EST
Manhattan Jaspers
Hawaii Rainbow Warriors
11/15/25 12AM
MANHAT
HAWAII
|
–
–
|
+740
|
+14 (-106)
|
O 155.5 (-108)
U 155.5 (-108)
|
CBB Past Picks
Remi—our in-house AI—prices every game and prop using multi-season priors, tempo/efficiency, injury/usage signals, and market movement.
We publish fair prices, recommended “buy-to” numbers, and confidence so you can bet prices, not teams.
This preview covers Missouri Tigers vs. Illinois Fighting Illini on December 22, 2025 at .
Odds shown reflect widely available numbers and may update closer to kickoff.
Want more? Check live edges, player props, and line moves on our CBB odds pages, and compare prices before you place a bet.
| CBB |
LEAN | %WIN | UNITS | RESULT |
|---|---|---|---|---|
| DRAKE@MIZZOU | DRAKE +6.5 | 53.50% | 2 | WIN |
| XAVIER@TEXAS | XAVIER -2.5 | 53.40% | 2 | WIN |
| UAB@MEMP | MEMP -3.5 | 54.00% | 2 | WIN |
| LVILLE@DUKE | LVILLE +6.5 | 53.10% | 2 | LOSS |
| ECU@UAB | UAB -5 | 53.60% | 2 | WIN |
| PURDUE@MICH | MICH +3 | 54.60% | 3 | WIN |
| CLEM@LVILLE | CLEM -120 | 56.10% | 3 | LOSS |
| COL@HOU | ANDREJ JAKIMOVSKI PTS + REB + AST - UNDER 15.5 | 53.70% | 2 | LOSS |
| FORD@GWASH | FORD +7 | 53.80% | 2 | WIN |
| SEATTLE@ABIL | ABIL +6 | 54.50% | 3 | WIN |
| BAMAST@TEXSOU | BAMAST -110 | 55.40% | 4 | WIN |
| OHIO@TOLEDO | TOLEDO +3 | 56.70% | 4 | WIN |
| UVA@GATECH | GATECH +1.5 | 53.70% | 2 | WIN |
| COLO@WVU | COLO +7.5 | 53.20% | 2 | WIN |
| USC@RUT | USC -115 | 54.00% | 2 | WIN |
| TEXAS@VANDY | VANDY -130 | 56.50% | 3 | LOSS |
| BUTLER@PROV | BUTLER -115 | 55.20% | 3 | WIN |
| IDAHO@MONTANA | MONTANA -6 | 53.50% | 2 | WIN |
| TROY@JMAD | TROY -125 | 55.60% | 2 | WIN |
| BELMONT@DRAKE | DRAKE -7.5 | 53.50% | 2 | LOSS |
| UCSD@UCDAV | UCSD -12.5 | 53.40% | 2 | LOSS |
| SIUE@SEMO | SEMO -2.5 | 54.80% | 3 | LOSS |
| ALCORN@ARKPB | ARKPB +6.5 | 56.00% | 4 | WIN |
| NORFLK@HOWARD | HOWARD +5.5 | 53.70% | 2 | LOSS |
| NKY@CLEVST | NKY +4.5 | 54.40% | 3 | LOSS |
| STNFRD@ND | STNFRD -125 | 56.40% | 3 | LOSS |
| TENN@OLEMISS | OLEMISS +2.5 | 54.30% | 3 | WIN |
| LSALLE@GMASON | GMASON -12 | 54.30% | 3 | LOSS |
| PITT@NCST | NCST +2.5 | 56.70% | 4 | WIN |
| IND@OREG | OREG -6.5 | 53.60% | 2 | WIN |
| FSU@UVA | UVA -4 | 54.40% | 3 | LOSS |
| ARK@VANDY | ARK +7.5 | 54.40% | 3 | WIN |
| SDGST@UNLV | UNLV +2.5 | 54.10% | 3 | WIN |
| EKTY@JVILLE | JVILLE -135 | 58.90% | 3 | WIN |
| MANHAT@NIAGARA | MANHAT -115 | 54.70% | 3 | WIN |
| MEMP@UAB | MEMP -115 | 54.90% | 3 | WIN |
| ILL@MICH | MICH -2.5 | 56.00% | 4 | LOSS |
| OKLA@OLEMISS | OKLA +7.5 | 54.50% | 3 | WIN |
| ARIZST@UTAH | ARIZST +8.5 | 54.60% | 3 | LOSS |
| GC@SEATTLE | GC -110 | 55.00% | 3 | WIN |
| PENN@CLMBIA | CLMBIA -122 | 57.50% | 4 | LOSS |
| IONA@NIAGARA | NIAGARA +1.5 | 54.30% | 3 | LOSS |
| MARIST@SACHRT | SACHRT -120 | 55.40% | 3 | WIN |
| CLEVST@WRIGHT | CLEVST +1.5 | 54.30% | 3 | LOSS |
| NDAK@STTHOM | STTHOM -10 | 54.30% | 3 | WIN |
| USD@WASHST | WASHST -12.5 | 55.20% | 4 | LOSS |
| CSBAK@LBEACH | CSBAK -130 | 59.70% | 4 | WIN |
| BU@LEHIGH | LEHIGH -135 | 57.70% | 3 | LOSS |
| DUQ@LSALLE | DUQ -125 | 56.70% | 3 | WIN |
| BYU@ARIZST | ARIZST +7.5 | 54.60% | 3 | LOSS |
| UTAHST@BOISE | BOISE -4 | 55.50% | 4 | WIN |